BDgene

SNP Report

Basic Info
Name rs2433320 dbSNP Ensembl
Location chr4:94449654 - 94449654(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.271765
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000317968, ENST00000318007, ENST00000359265, ENST00000380180, ENST00000437932, ENST00000503974, ENST00000504489, ENST00000509333, ENST00000512274, ENST00000514830, ENST00000542407, ENST00000615540, ENST00000627587)
No. of Studies 3 (Positive: 0; Negative: 3; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Shi, J., 2008 (c) G/A TDT P-value = 0.13 TDT P-value = 0.13 Our association analysis showed no single SNP associated wit...... Our association analysis showed no single SNP associated with BP. More... Negative
Squassina, A.,2008 A/G Allelic P-value = 0.261; OR=1.1; genotypic P-value = 0.055 Allelic P-value = 0.261; OR=1.1; genotypic P-value = 0.055 We found an association trend for the genotype GG at this SN...... We found an association trend for the genotype GG at this SNP, with higher frequency in BD than in controls. More... Negative
Zhao, T.,2009 A/G Allelic association: among patients and controls, P-value = ...... Allelic association: among patients and controls, P-value = 0.44, OR (95% CI)=1.10(0.86-1.41); among patients with bipolar disorder I and controls, P-value = 0.28, OR (95% CI)=1.15(0.89-1.49). Genotypic Association: among patients and controls, P-value = 0.45; among patients with bipolar disorder I and controls, P-value = 0.25 More... No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PDLIM5 PDZ and LIM domain 5 4q22 5(4/1/0)

SNPs in LD with rs2433320 (count: 8) View in gBrowse (chr4:94439195..94489213 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 8)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016