SNP Report

Basic Info

Name	rs2439300 dbSNP Ensembl
Location	chr8:32575586 - 32575586(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.288938
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000519301, ENST00000520407, ENST00000521670, ENST00000523079, ENST00000523534, ENST00000631040)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.4668 for BP, Individual P-value = 0.9...... Individual P-value = 0.4668 for BP, Individual P-value = 0.9469 for SCZ and BP More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs2439300 (count: 7) View in gBrowse (chr8:32575586..32586748 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs17721282	intron_variant	0.834[CEU]
rs10503921	intron_variant	0.836[CEU]
rs17721372	intron_variant	0.97[TSI]
rs2466062	intron_variant	0.815[TSI]
rs10954859	intron_variant	0.824[CEU]; 1.0[TSI]
rs10954858	intron_variant	0.836[CEU]
rs4298457	intron_variant	0.836[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.4052 for SCZ , Individual P-value = 0.9469 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)