Gene Report

Basic Info
Approved Symbol ALG9
Previous Symbol DIBD1
Approved Name ALG9, alpha-1,2-mannosyltransferase
Previous Name disrupted in bipolar affective disorder 1, "asparagine-linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase)", "asparagine-linked glycosylation 9, alpha- 1,2-mannosyltransferase homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase)", "asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae)"
Name Alias dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase, "dolichyl-P-Man:Man(8)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase", "dol-P-Man dependent alpha-1,2-mannosyltransferase"
Location 11q23
Position chr11:111782195-111871581, -1
External Links HGNC: 15672
Entrez Gene: 79796
Ensembl: ENSG00000086848
UCSC: uc031yew.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Baysal, B. E., 2006 SNP: rs10502151
Haplotype: ALG9_D11S5028 - rs10502151(1-1), ALG9_D11S5028 - rs10502151(3-1), ALG9_D11S5028 - rs10502151(4-1), ALG9_D11S5028 - rs10502151(5-1), ALG9_D11S5028 - rs10502151(2-2), ALG9_D11S5028 - rs10502151(5-2), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(1-1-1), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(3-1-1), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(4-1-1), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(5-1-1), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(2-1-4), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(2-2-2), ALG9_D11S5028 - rs10502151 - ALG9_D11S5027(2-2-3)
Other variant: ALG9_D11S5025, ALG9_D11S5026, ALG9_D11S5027, ALG9_D11S5028
These results suggest that common variations in ALG9 do not play a major role in predisposition to bipolar affective disorder Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 2)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 2)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 9)

Literature-origin SNPs (count: 1)

LD-proxies (count: 8)

Gene related CNVs (count: 0)

Gene related other variants (count: 4)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr11:111782195..111871581 View in gBrowse
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