BDgene

SNP Report

Basic Info
Name rs1785437 dbSNP Ensembl
Location chr21:44401911 - 44401911(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.292133
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000300481, ENST00000300482, ENST00000397928, ENST00000397932, ENST00000498430); non_coding_transcript_variant(ENST00000498430)
No. of Studies 3 (Positive: 1; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Xu, C., 2006 T/C allelic P-value = 0.006, corrected P-value = 0.042, X2<...... allelic P-value = 0.006, corrected P-value = 0.042, X2=7.43, genotypic P-value = 0.017, X2=8.2 in BD; allelic P-value = 0.019, X2=5.48, genotypic P-value = 0.043, X2=6.3 in BD-I ; allelic P-value = 0.045, X2=4.01, genotypic P-value = 0.037, X2=6.6 in BD-II More... Positive
McQuillin, A., 2006 P-value = 0.28, Pearson's X2=1.17 P-value = 0.28, Pearson's X2=1.17 Negative
Xu, C.,2009 C TDT: in BD families, X2=0.06, P-value = 0.812; in...... TDT: in BD families, X2=0.06, P-value = 0.812; in BD-I families, X2=0.22, P-value = 0.638; in BD-II families, X2=0.23, P-value = 0.629 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TRPM2 transient receptor potential cation channel, subfamily M, member 2 21q22.3 5(3/2/0)

SNPs in LD with rs1785437 (count: 0) View in gBrowse (chr21:44401911..44401911 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)