SNP Report

Basic Info

Name	rs2439273 dbSNP Ensembl
Location	chr8:32632792 - 32632792(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.169329
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000518206, ENST00000519301, ENST00000520407, ENST00000521670, ENST00000522569, ENST00000523079, ENST00000523534, ENST00000631040); non_coding_transcript_variant(ENST00000522569)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	G/A		Total BPI vs. controls: X²=4.02, OR=1.39, 95%CI=1...... Total BPI vs. controls: X²=4.02, OR=1.39, 95%CI=1.00-1.91, Bonf P-value=1; BPI-P vs. controls: X²=2, OR=1.3, 95%CI=0.90-1.87, Bonf P-value=1; BPI-NP vs. controls: X²=2.05, OR=1.43, 95%CI=0.87-2.34, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs2439273 (count: 4) View in gBrowse (chr8:32607421..32632792 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2466059	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2466061	intron_variant; non_coding_transcript_variant	0.877[CHB]; 1.0[JPT]
rs2466092	intron_variant	0.888[CHB]
rs2439276	intron_variant; non_coding_transcript_variant	0.877[CHB]; 1.0[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)