BDgene

SNP Report

Basic Info
Name rs12668354 dbSNP Ensembl
Location chr7:21492273 - 21492273(1)
Variant Alleles C/A
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.186502
Functional Annotation intron_variant; NMD_transcript_variant.
Consequence to Transcript intron_variant(ENST00000222584, ENST00000448246); NMD_transcript_variant(ENST00000448246)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Zhou, X.,2009 A/C Allelic association: Caucasian Families for Bipolar Disorder...... Allelic association: Caucasian Families for Bipolar Disorder: TDT: Risk allele is C, MAF=0.33, P-value = 0.022; Chinese Case-Controls for Bipolar Disorder: Risk allele is C, MAF=0.09, P-value = 0.163 More... Significant association was observed in Caucasian Families f...... Significant association was observed in Caucasian Families for Bipolar Disorder. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SP4 Sp4 transcription factor 7p15 1(1/0/0)

SNPs in LD with rs12668354 (count: 22) View in gBrowse (chr7:21434992..21513377 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 22)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)