SNP Report

Basic Info

Name	rs2619538 dbSNP Ensembl
Location	chr6:15664978 - 15664978(1)
Variant Alleles	A/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.408347
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000338950, ENST00000344537, ENST00000355917, ENST00000506844, ENST00000510395, ENST00000511762, ENST00000513680, ENST00000515875, ENST00000622898, LRG_588t1, LRG_588t2)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Joo, E. J., 2007	A/T		Fisher's exact test, allelic P-value = 0.305 for BPD I, P-va...... Fisher's exact test, allelic P-value = 0.305 for BPD I, P-value = 0.437 for BPD I and II, P-value = 0.461 for BPD I, II and SA; genotypic P-value = 0.464 for BPD I, P-value = 0.501 for BPD I and II, P-value = 0.548 for BPD I, II and SA More...	no significant association was detected no significant association was detected	Negative
Raybould, R.,2005	T/A		Single-Marker Analysis: for all BPI, allele P-value = 0.360;...... Single-Marker Analysis: for all BPI, allele P-value = 0.360; for BPI with Psychotic Symptoms in 50% or More of Episodes, allele P-value = 0.004 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DTNBP1	dystrobrevin binding protein 1	6p22.3	8(4/3/1)

SNPs in LD with rs2619538 (count: 9) View in gBrowse (chr6:15520547..15755775 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2209863		1.0[JPT]
rs7755766		1.0[CHB]; 1.0[JPT]
rs9296989		1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs17409155		1.0[JPT]
rs2181435		1.0[CHB]
rs6914388		1.0[CHB]; 1.0[JPT]
rs13201824	3_prime_UTR_variant; downstream_gene_variant	1.0[JPT]
rs1047631	3_prime_UTR_variant; downstream_gene_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]
rs17473314		1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)