Gene Report

Basic Info
Approved Symbol ZDHHC8
Symbol Alias ZNF378, KIAA1292
Approved Name zinc finger, DHHC-type containing 8
Location 22q11.21
Position chr22:20129456-20148007, 1
External Links HGNC: 18474
Entrez Gene: 29801
Ensembl: ENSG00000099904
UCSC: uc002zrr.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Otani, K.,2005(b) SNP: rs175170, rs175174
Haplotype: rs175170 - rs175174()
These data suggest that the ZDHHC8 gene may not be associated with susceptibility to BPD or schizophrenia, at least in a Japanese population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 2)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 5)

Literature-origin SNPs (count: 2)

LD-proxies (count: 3)

Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 10)

Gene relationship with MDD

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Region: chr22:20129456..20148007 View in gBrowse
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