SNP Report

Basic Info

Name	rs11759115 dbSNP Ensembl
Location	chr6:37673254 - 37673254(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.153554
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000434837, ENST00000505425, ENST00000515437)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Li, J.,2011(a)	C/T		Single SNP analyses: allele, P-value = 0.3301, OR[95%CI]=1.0...... Single SNP analyses: allele, P-value = 0.3301, OR[95%CI]=1.0822[0.9232, 1.2686], genotype, P-value = 0.506 for BP More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6p21	1(1/0/0)

SNPs in LD with rs11759115 (count: 1) View in gBrowse (chr6:37673254..37675885 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs4714091		intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.0131(0.1902), OR[95%CI]=0.8055[0.6789, 0.9558], genotype, P-value = 0.0026(0.0086 after permutations) for SZ	Significant association was observed in SZ.	Positive

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.5261, OR[95%CI]=0.9485[0.8054, 1.1170], genotype, P-value = 0.8089 for MDD	No significant association was observed.	Negative