BDgene

SNP Report

Basic Info
Name rs1011313 dbSNP Ensembl
Location chr6:15633201 - 15633201(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.109026
Functional Annotation intron_variant; NMD_transcript_variant.
Consequence to Transcript intron_variant(ENST00000338950, ENST00000344537, ENST00000355917, ENST00000506844, ENST00000510395, ENST00000511762, ENST00000513680, ENST00000515875, ENST00000622898, LRG_588t1, LRG_588t2); NMD_transcript_variant(ENST00000506844, ENST00000510395, ENST00000513680, ENST00000515875)
No. of Studies 4 (Positive: 0; Negative: 4; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Perlis, 2008 Mean X2=3.08, P-value = 0.27 in gene-based associ...... Mean X2=3.08, P-value = 0.27 in gene-based association tests More... Negative
Breen, G., 2006 data not shown data not shown did not show individual genotypic association with bipolar I...... did not show individual genotypic association with bipolar I disorder More... Negative
Gaysina, D.,2009 A/G chi-square test: 1.Between Bipolar Disorder and Control Grou...... chi-square test: 1.Between Bipolar Disorder and Control Groups: genotype: X2=3.19, P-value = 0.203; allele: X2=0.34, P-value = 0.559 2.In Bipolar I Disorder (BID) and Bipolar II Disorder (BIID) Groups: allele: X2=0.009, P-value = 0.923 More... No significant differences was observed between the groups o...... No significant differences was observed between the groups of BD-I and BD-II.No significant association was observed in the BD group. More... Negative
Pae, C. U., 2007 (a) COCAPHASE P-value > 0.05 COCAPHASE P-value > 0.05 No significant association was observed in single marker ana...... No significant association was observed in single marker analyses More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DTNBP1 dystrobrevin binding protein 1 6p22.3 8(4/3/1)

SNPs in LD with rs1011313 (count: 4) View in gBrowse (chr6:15584682..15729836 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)