BDgene

SNP Report

Basic Info
Name rs10838524 dbSNP Ensembl
Location chr11:45848626 - 45848626(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.338458
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000417225, ENST00000443527, ENST00000473199, ENST00000496571, ENST00000532390, ENST00000616080, ENST00000616623); non_coding_transcript_variant(ENST00000473199, ENST00000496571, ENST00000532390)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Sjoholm, L. K.,2010 A/G Association analysis: allele P-value = 0.0076, empirical P-v...... Association analysis: allele P-value = 0.0076, empirical P-value = 0.022, OR [95% CI]=1.42[1.1021.83]; genotype, Cochran-Armitage trend P-value = 0.0076, Logistic regression: Dominant model, P-value = 0.0081, OR[95%CI]=1.79[1.1622.75], Recessive model, P-value = 0.1, OR[95%CI]=1.42[0.9322.16] More... Significant association was found in BD. Significant association was found in BD. Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CRY2 cryptochrome circadian clock 2 11p11.2 5(3/2/0)

SNPs in LD with rs10838524 (count: 6) View in gBrowse (chr11:45818158..45857441 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)