SNP Report

Basic Info

Name	rs2224721 dbSNP Ensembl
Location	chr13:46858019 - 46858019(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.33726
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000430913, ENST00000452352, ENST00000455126); intron_variant(ENST00000378688, ENST00000542664, ENST00000543956)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z.,2009			single marker association: Asymptotic P-value = 0.02, Empiri...... single marker association: Asymptotic P-value = 0.02, Empirical P-value = 0.02, Odds ratio=1.53 More...	Significant association was observed in the BP group. Significant association was observed in the BP group.	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	13q14-q21	22(7/15/0)
HTR2A-AS1	HTR2A antisense RNA 1	13q14.2	Mapped by Literature SNP

SNPs in LD with rs2224721 (count: 1) View in gBrowse (chr13:46858019..46859220 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs9316233		downstream_gene_variant; intron_variant	0.838[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)