BDgene

SNP Report

Basic Info
Name rs2282586 dbSNP Ensembl
Location chr11:120987701 - 120987701(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.324081
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000527524); downstream_gene_variant(ENST00000438375)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Pickard, B. S., 2006 A/G P-value = 0.02 between BPD cases and controls; P-value = 0....... P-value = 0.02 between BPD cases and controls; P-value = 0.058 between all cases and controls More... it was associated with bipolar disorder it was associated with bipolar disorder Positive
Yosifova, A.,2009 A/G Allelic association: P-value = 0.27 Allelic association: P-value = 0.27 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRIK4 glutamate receptor, ionotropic, kainate 4 11q23.3 2(1/1/0)

SNPs in LD with rs2282586 (count: 5) View in gBrowse (chr11:120978353..120991380 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Pickard, B. S., 2006 P-value = 0.358 between SCZ cases and controls; P-value = 0.058 between all cases and controls Negative

Overlap with MDD from cross-disorder studies (count: 0)