Gene Report

Basic Info
Approved Symbol DLG1
Symbol Alias SAP97, SAP-97, hdlg, DLGH1, dJ1061C18.1.1
Approved Name discs, large homolog 1 (Drosophila)
Previous Name discs, large (Drosophila) homolog 1
Name Alias discs large homolog 1, "presynaptic protein SAP97", "synapse-associated protein 97"
Location 3q29
Position chr3:197042560-197299300, -1
External Links HGNC: 2900
Entrez Gene: 1739
Ensembl: ENSG00000075711
UCSC: uc003fxn.4
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Schosser, A.,2011 SNP: rs338217
Haplotype: rs1134986 - rs338217()
No significant association was observed. Negative Comment on Study
Noor A., 2014 Selected stringent CNV related to this gene is validated by qPCR from BD case data. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 84)

GO terms by PBA (count: 7)

GO terms by database search (count: 77)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 68)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 2)

LD-proxies (count: 4)

Gene related CNVs (count: 2)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr3:197042560..197299300 View in gBrowse
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