BDgene

SNP Report

Basic Info
Name rs10997875 dbSNP Ensembl
Location chr10:67920067 - 67920067(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.499201
Functional Annotation downstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000212015, ENST00000277817, ENST00000373700, ENST00000395198, ENST00000403579, ENST00000406900, ENST00000412272, ENST00000427635, ENST00000432464, ENST00000473533)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kishi, T.,2011(a) T/C For BP, X2 test: genotype, X2(2df)=3.2...... For BP, X2 test: genotype, X2(2df)=3.26, P-value = 0.196; allele, X2(2df)=0.921, P-value = 0.337 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 10q21.3 Mapped by Literature SNP
SIRT1 sirtuin 1 10q21 1(0/1/0)

SNPs in LD with rs10997875 (count: 59) View in gBrowse (chr10:67839572..68088541 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 59)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kishi, T.,2011(a) For SZ, X2 test:genotype, X2(2df)=2.84, P-value = 0.242;allele, X2(2df)=0.00002, P-value = 0.996 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016