Gene Report

Approved Symbol	GRIK4
Previous Symbol	GRIK
Symbol Alias	GluK4, KA1
Approved Name	glutamate receptor, ionotropic, kainate 4
Location	11q23.3
Position	chr11:120511759-120988904, 1
External Links	HGNC: 4582 Entrez Gene: 2900 Ensembl: ENSG00000149403 UCSC: uc009zaw.2
No. of Studies	2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Pickard, B. S., 2006	SNP: rs1944522, rs1954787, rs2000869, rs2156635, rs2187495, rs2276319, rs2282586, rs2852217, rs3132780, rs3133226, rs3133855, rs4245040, rs433110, rs4430518, rs4582985, rs4935752, rs513548, rs602104, rs6589832, rs6589846, rs7111184, rs7925270, rs7928347, rs879602, rs948028, rs949054, rs949056 Haplotype: rs1954787 - rs4935752(), rs1954787 - rs4935752 - rs6589846(), rs1954787 - rs4935752 - rs6589846 - rs4430518(), rs2000869 - rs7479743(), rs2000869 - rs7479743 - rs6589832(), rs2000869 - rs7479743 - rs6589832 - rs7925270(), rs2156635 - rs949056(), rs2156635 - rs949056 - rs949054(), rs2156635 - rs949056 - rs949054 - rs602104(), rs2187495 - rs3132780(), rs2187495 - rs3132780 - rs948028(), rs2187495 - rs3132780 - rs948028 - rs2852217(), rs2276319 - rs513548(), rs2276319 - rs513548 - rs2282586(), rs2276319 - rs513548 - rs2282586(A-T-G), rs2276319 - rs513548 - rs2282586 - rs1944522(), rs2276319 - rs513548 - rs2282586 - rs1944522(A-T-G-C), rs2282586 - rs1944522(), rs2282586 - rs1944522(G-C), rs2852217 - rs879602(), rs2852217 - rs879602 - rs1954787(), rs2852217 - rs879602 - rs1954787 - rs4935752(), rs3132780 - rs948028(), rs3132780 - rs948028 - rs2852217(), rs3132780 - rs948028 - rs2852217 - rs879602(), rs3133226 - rs2187495(), rs3133226 - rs2187495 - rs3132780(), rs3133226 - rs2187495 - rs3132780 - rs948028(), rs3133855 - rs3133226(), rs3133855 - rs3133226 - rs2187495(), rs3133855 - rs3133226 - rs2187495 - rs3132780(), rs4245040 - rs7928347(), rs4245040 - rs7928347 - rs2000869(), rs4245040 - rs7928347 - rs2000869 - rs7479743(), rs433110 - rs7111184(), rs433110 - rs7111184 - rs2156635(), rs433110 - rs7111184 - rs2156635 - rs949056(), rs4430518 - rs433110(), rs4430518 - rs433110 - rs7111184(), rs4430518 - rs433110 - rs7111184 - rs2156635(), rs4935752 - rs6589846(), rs4935752 - rs6589846 - rs4430518(), rs4935752 - rs6589846 - rs4430518 - rs433110(), rs513548 - rs2282586(), rs513548 - rs2282586(T-G), rs513548 - rs2282586 - rs1944522(), rs513548 - rs2282586 - rs1944522(T-G-C), rs602104 - rs2276319(), rs602104 - rs2276319(C-A), rs602104 - rs2276319 - rs513548(), rs602104 - rs2276319 - rs513548 - rs2282586(), rs602104 - rs2276319 - rs513548 - rs2282586(C-A-T-G), rs6589832 - rs7925270(), rs6589832 - rs7925270 - rs3133855(), rs6589832 - rs7925270 - rs3133855(G-C-T), rs6589832 - rs7925270 - rs3133855 - rs3133226(), rs6589832 - rs7925270 - rs3133855 - rs3133226(G-C-T-C), rs6589846 - rs4430518(), rs6589846 - rs4430518 - rs433110(), rs6589846 - rs4430518 - rs433110 - rs7111184(), rs7111184 - rs2156635(), rs7111184 - rs2156635 - rs949056(), rs7111184 - rs2156635 - rs949056 - rs949054(), rs7479743 - rs6589832(), rs7479743 - rs6589832 - rs7925270(), rs7479743 - rs6589832 - rs7925270 - rs3133855(), rs7479743 - rs6589832 - rs7925270 - rs3133855(C-G-C-T), rs7925270 - rs3133855(), rs7925270 - rs3133855 - rs3133226(), rs7925270 - rs3133855 - rs3133226 - rs2187495(), rs7928347 - rs2000869(), rs7928347 - rs2000869 - rs7479743(), rs7928347 - rs2000869 - rs7479743 - rs6589832(), rs879602 - rs1954787(), rs879602 - rs1954787 - rs4935752(), rs879602 - rs1954787 - rs4935752 - rs6589846(), rs948028 - rs2852217(), rs948028 - rs2852217 - rs879602(), rs948028 - rs2852217 - rs879602 - rs1954787(), rs949054 - rs602104(), rs949054 - rs602104(T-C), rs949054 - rs602104 - rs2276319(), rs949054 - rs602104 - rs2276319(T-C-A), rs949054 - rs602104 - rs2276319 - rs513548(), rs949056 - rs949054(), rs949056 - rs949054 - rs602104(), rs949056 - rs949054 - rs602104(A-T-C), rs949056 - rs949054 - rs602104 - rs2276319(), rs949056 - rs949054 - rs602104 - rs2276319(A-T-C-A)	Findings of cytogenetic and genetic evidence supported a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder	Positive	Comment on Study
Yosifova, A.,2009	SNP: rs1944522, rs2282586	No SNP of this gene had significant association with BD in our population.	Negative	Comment on Study

Region: chr11:120511759..120988904 View in gBrowse