BDgene

SNP Report

Basic Info
Name rs9315885 dbSNP Ensembl
Location chr13:42068674 - 42068674(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.414736
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000403865, ENST00000611224); intron_variant(ENST00000261491, ENST00000337343, ENST00000379274)
No. of Studies 6 (Positive: 0; Negative: 6; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? YES

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Zeng, Z.,2011 T Allelic association: P-value = 0.453, permutated P-value = 0...... Allelic association: P-value = 0.453, permutated P-value = 0.995 for BPD; P-value = 0.256, permutated P-value = 0.915 for BPDI More... No significant association was observed in BD. No significant association was observed in BD. Negative
Ollila, H. M.,2009 T/C FBAT: P-value = 0.069024 FBAT: P-value = 0.069024 No significant association was observed No significant association was observed Negative
Takata, A.,2011(a) T/C Fisher's exact test: allele P-value = 0.9166, genotype P-val...... Fisher's exact test: allele P-value = 0.9166, genotype P-value = 0.9094 More... No significant association was observed in BD. No significant association was observed in BD. Negative
Squassina, A.,2009 T Alelle association: P-value = 0.035permutation P-value = 0.0...... Alelle association: P-value = 0.035permutation P-value = 0.073 More... No significant association was observed No significant association was observed Negative
Baum, A. E., 2008 (a) T P-value = 0.005 when genotyped individually in the test samp...... P-value = 0.005 when genotyped individually in the test sample (NIMH); P-value = 0.006 when individually genotyped in the Replication sample (German); P-value = 0.0001 in the combined dataset. OR (95% CI)=1.26 (1.12-1.42) More... significant at the P < 0.05 level in both samples. significant at the P < 0.05 level in both samples. Negative
Baum, A. E., 2008 (b) T Random effects P-value = 0.042; DerSimonian-Laird (random e...... Random effects P-value = 0.042; DerSimonian-Laird (random effects) OR (95% CI)=1.18 (1.01-1.37) More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DGKH diacylglycerol kinase, eta 13q13.3 6(3/3/0)
MAPK6PS3 mitogen-activated protein kinase 6 pseudogene 3 13q14.13 Mapped by Literature SNP

SNPs in LD with rs9315885 (count: 11) View in gBrowse (chr13:42068410..42086709 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 11)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Zeng, Z.,2011 Allelic association:P-value = 0.014, permutated P-value = 0.127 for SCZ No significant association was observed after permutation. Negative

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Zeng, Z.,2011 Allelic association:P-value > 0.05 for MDD. No significant association was observed after permutation. Negative