Gene Report

Basic Info
Approved Symbol SNAP29
Symbol Alias SNAP-29, CEDNIK
Approved Name synaptosomal-associated protein, 29kDa
Previous Name synaptosomal-associated protein, 29kD
Name Alias soluble 29 kDa NSF attachment protein
Location 22q11.21
Position chr22:20858983-20891218, 1
External Links HGNC: 11133
Entrez Gene: 9342
Ensembl: ENSG00000099940
UCSC: uc011ahw.2
No. of Studies 3 (Positive: 1; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 3)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Hu, X.,2010 Haplotype: rs10123629 - rs165596(), rs10123629 - rs178069(), rs10124883 - rs165596(), rs10124883 - rs178069() Our results indicate that interactions between neurological pathway-related genes ASTN2 and SNAP29 or ASTN2 and PIK4CA, or other genes in linkage disequilibrium with any genes in these pairs, were risk factors of BPD, in both Caucasian and Chinese Han populations. Positive Comment on Study
Fallin, M. D.,2005 4 SNP typed, Median D'=1, Median r<sup>2</sup> =0.98, 1 LD blocks, 0.98 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA... This gene is not suggestive to BP. Negative Comment on Study
Saito, T.,2001 Other variant: SNAP29_exon1_56T>C, SNAP29_exon1_92A>G, SNAP29_promoter_-849G>A No significant difference was found in patients with BPD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 17)

GO terms by PBA (count: 2)

GO terms by database search (count: 15)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 12)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

Gene related other variants (count: 3)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

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Region: chr22:20858983..20891218 View in gBrowse
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