BDgene

SNP Report

Basic Info
Name rs510110 dbSNP Ensembl
Location chr18:10540435 - 10540435(1)
Variant Alleles A/C
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.363019
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000582472); intron_variant(ENST00000322897, ENST00000580224, ENST00000580483, ENST00000583367); NMD_transcript_variant(ENST00000580224, ENST00000580483); non_coding_transcript_exon_variant(ENST00000582978); non_coding_transcript_variant(ENST00000582978, ENST00000583367)
No. of Studies 3 (Positive: 1; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Weller, A. E., 2006 A/C genotypic P-value = 0.046, allelic P-value = 0.355 genotypic P-value = 0.046, allelic P-value = 0.355 showed a nominal, statistically significant association with...... showed a nominal, statistically significant association with BPD at the genotype frequency level but not at the allele frequency level More... Positive
Yosifova, A.,2009 C/A Allelic association: P-value = 0.25 Allelic association: P-value = 0.25 No significant association was observed No significant association was observed Negative
Li, X.,2009 A/C C 1.BD patients and control: Allele distribution: Permutated P...... 1.BD patients and control: Allele distribution: Permutated P-value = 0.8115, Genotype distribution: P-value = 0.1981; 2.BD-I patients and control: Allele distribution: Permutated P-value = 0.6151, Genotype distribution: P-value = 0.0585 More... No significant association was observed in BD group or BD-I ...... No significant association was observed in BD group or BD-I group. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 18p11.21 3(2/1/0)

SNPs in LD with rs510110 (count: 23) View in gBrowse (chr18:10515297..10556839 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 23)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016