SNP Report

Basic Info

Name	rs7178270 dbSNP Ensembl
Location	chr15:78628735 - 78628735(1)
Variant Alleles	C/G/T
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.330871
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000559120, ENST00000559849, ENST00000560511); intron_variant(ENST00000261751, ENST00000412074)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2007	G/C		TDT P-value = 0.46 of Allelic Association With Bipolar Disor...... TDT P-value = 0.46 of Allelic Association With Bipolar Disorder in the Combined Sample More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNB4	cholinergic receptor, nicotinic, beta 4 (neuronal)	15q24	2(1/1/0)

SNPs in LD with rs7178270 (count: 1) View in gBrowse (chr15:78619661..78628735 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs1878399		downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.805[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)