BDgene

SNP Report

Basic Info
Name rs907094 dbSNP Ensembl
Location chr17:39634118 - 39634118(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele G
Minor Allele Frequence 0.484425
Functional Annotation downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000580772, ENST00000582680); intron_variant(ENST00000254079, ENST00000394265, ENST00000394267, ENST00000492037, ENST00000579000, ENST00000580029, ENST00000580825, ENST00000583446); non_coding_transcript_variant(ENST00000492037, ENST00000580029, ENST00000583446); upstream_gene_variant(ENST00000336308, ENST00000394250, ENST00000544210, ENST00000577248, ENST00000578232, ENST00000578254, ENST00000578577, ENST00000579479, ENST00000580551, ENST00000580611, ENST00000581894, ENST00000583582, ENST00000583718, ENST00000585214)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Yoshimi, A., 2008 T/C C Genotypic P-value = 0.036, Armitage's P-value = 0.010. allel...... Genotypic P-value = 0.036, Armitage's P-value = 0.010. allelic P-value = 0.010 in the first BD sample set. Genotypic P-value = 0.565, Armitage's P-value = 0.731. allelic P-value = 0.734 in the second BD sample set. More... significant associations with bipolar disorder were observed significant associations with bipolar disorder were observed Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
STARD3 StAR-related lipid transfer (START) domain containing 3 17q11-q12 Mapped by Literature SNP
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 17q12 1(0/1/0)

SNPs in LD with rs907094 (count: 36) View in gBrowse (chr17:39611200..39683240 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 36)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Yoshimi, A., 2008 Genotypic P-value = 0.518, Armitage's P-value = 0.673. allelic P-value = 0.681 in SZ. Single-marker in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia. Negative

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016