BDgene

SNP Report

Basic Info
Name rs9990 dbSNP Ensembl
Location chr10:62808178 - 62808178(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.324281
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000373783); downstream_gene_variant(ENST00000242480, ENST00000411732, ENST00000439032); upstream_gene_variant(ENST00000425290)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kim, S. H.,2011 C/T For BD, chi-square tests: allele, OR=1.193, X2=2....... For BD, chi-square tests: allele, OR=1.193, X2=2.6714, P-value = 0.1022, P-value(permutation)=0.4195; Fisher's exact test, genotype, X2=3.5156, P-value = 0.1724 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
EGR2 early growth response 2 10q21.1 3(1/2/0)
ADO 2-aminoethanethiol (cysteamine) dioxygenase 10q21.3 Mapped by Literature SNP

SNPs in LD with rs9990 (count: 4) View in gBrowse (chr10:62803942..62808178 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kim, S. H.,2011 For SZ, chi-square tests:allele, OR=1.244, X2=3.3587, P-value = 0.0668, P-value(permutation)=0.305;Fisher's exact test, genotype, X2=5.4069, P-value = 0.067 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)