SNP Report

Basic Info

Name	rs2241802 dbSNP Ensembl
Location	chr8:28527195 - 28527195(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.457668
Functional Annotation	synonymous_variant; upstream_gene_variant.
Consequence to Transcript	synonymous_variant(ENST00000240093, ENST00000537916); upstream_gene_variant(ENST00000365541)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hashimoto, R.,2005(b)	G/A		Allelic association: P-value = 0.94 for BP Allelic association: P-value = 0.94 for BP	No significant associations were found in BD. No significant associations were found in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FZD3	frizzled class receptor 3	8p21	1(0/1/0)
RNA5SP259	RNA, 5S ribosomal pseudogene 259	8p21.1	Mapped by Literature SNP

SNPs in LD with rs2241802 (count: 16) View in gBrowse (chr8:28498190..28578151 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2043182	intron_variant; upstream_gene_variant	0.901[CHB]; 0.901[JPT]
rs6980605	intron_variant; upstream_gene_variant	0.905[CHB]; 0.907[CHD]; 0.951[JPT]
rs17517918	intron_variant	0.906[CHB]; 0.952[JPT]
rs6984625	intron_variant	0.906[CHB]; 0.908[JPT]
rs11779401	downstream_gene_variant	0.906[CHB]; 0.907[CHD]; 0.908[JPT]
rs13275556	intron_variant	0.862[CHB]; 0.93[CHD]; 0.908[JPT]
rs8042	3_prime_UTR_variant	0.906[CHB]; 0.908[JPT]
rs4732642	3_prime_UTR_variant	0.906[CHB]; 0.908[JPT]
rs4732863	3_prime_UTR_variant; downstream_gene_variant	0.904[CHB]; 0.927[CHD]; 0.908[JPT]
rs7833751	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs6997072	downstream_gene_variant; intron_variant	0.906[CHB]; 0.929[CHD]; 0.905[JPT]
rs13260884	intron_variant; upstream_gene_variant	0.906[CHB]; 0.929[CHD]; 0.908[JPT]
rs4732861	downstream_gene_variant; intron_variant	0.807[CHB]; 0.908[JPT]
rs2323022	intron_variant	0.906[CHB]; 0.908[JPT]
rs2323021	intron_variant	0.905[CHB]; 0.904[JPT]
rs11775139	intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Hashimoto, R.,2005(b)	Allelic association:P-value = 0.85 for SZ	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Hashimoto, R.,2005(b)	Allelic association:P-value = 0.96 for MDD	No association was observed in MDD.	Negative