BDgene

Gene Report

Basic Info
Approved Symbol NAPEPLD
Symbol Alias FMP30, C7orf18, NAPE-PLD
Approved Name N-acyl phosphatidylethanolamine phospholipase D
Name Alias chromosome 7 open reading frame 18, N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Location 7q22.1
Position chr7:103099776-103149560, -1
External Links HGNC: 21683
Entrez Gene: 222236
Ensembl: ENSG00000161048
UCSC: uc003vbd.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Pisanu, C., 2013 SNP: rs17605251, rs11487077, rs12540583, rs6465903, rs7789727
Haplotype: rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(A-A-A-A-C), rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(A-G-A-A-C), rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(T-A-C-A-A), rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(T-A-A-C-C), rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(T-A-A-A-C), rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583(T-A-A-A-A)
Other variant: rs13232194
As a whole, our results do not support a clear role of NAPE-PLD in BD and lithium response. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 0)

GO terms by database search (count: 8)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 5)

LD-proxies (count: 1)


Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr7:103099776..103149560 View in gBrowse
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