BDgene

SNP Report

Basic Info
Name rs140681 dbSNP Ensembl
Location chr15:26937065 - 26937065(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.136781
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000335625, ENST00000355395, ENST00000400081, ENST00000541819, ENST00000555182)
No. of Studies 2 (Positive: 2; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Otani, K.,2005(a) G/A Chi-square test: for BPD, genotype P-value = 0.086, allele P...... Chi-square test: for BPD, genotype P-value = 0.086, allele P-value = 0.084; for BPD1, genotype P-value = 0.02, allele P-value = 0.024; for BPD2, genotype P-value = 0.98, allele P-value = 0.87 More... Significant association was observed in BPD1. Significant association was observed in BPD1. Positive
Yosifova, A.,2009 A/G Allelic association: 1st screening: P-value = 0.048, 2nd scr...... Allelic association: 1st screening: P-value = 0.048, 2nd screening: P-value = 0.32, total: P-value = 0.55 More... Significant association was observed in 1st screening. Significant association was observed in 1st screening. Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 15q12 6(6/0/0)
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 15q12 3(1/2/0)

SNPs in LD with rs140681 (count: 0) View in gBrowse (chr15:26937065..26937065 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)