BDgene

SNP Report

Basic Info
Name rs12772424 dbSNP Ensembl
Location chr10:113120792 - 113120792(1)
Variant Alleles A/T
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.411741
Functional Annotation intron_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000346198, ENST00000352065, ENST00000355717, ENST00000355995, ENST00000369395, ENST00000369397, ENST00000534894, ENST00000536810, ENST00000538897, ENST00000542695, ENST00000543371, ENST00000545257, ENST00000627217, ENST00000629706); upstream_gene_variant(ENST00000349937)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Cuellar-Barboza, A. B., 2016 T SNP main effect: P-value=1, OR=0.67; SNP-BMI interaction: P...... SNP main effect: P-value=1, OR=0.67; SNP-BMI interaction: P-value=0.011, OR=1.04 More... Seven out of the 26 genotyped TCF7L2 SNPs showed a significa...... Seven out of the 26 genotyped TCF7L2 SNPs showed a significant SNP–BMI interaction effect, with p < 0.05. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 1(1/0/0)

SNPs in LD with rs12772424 (count: 0) View in gBrowse (chr10:113120792..113120792 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)