BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Gene Report

Basic information

Related studies

Functional annotation

Related other genetic factors

Overlap with SZ and MDD

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Basic Info

Approved Symbol	PLCXD3
Approved Name	phosphatidylinositol-specific phospholipase C, X domain containing 3
Location	5p13.1
Position	chr5:41306954-41510628, -1
External Links	HGNC: 31822 Entrez Gene: 345557 Ensembl: ENSG00000182836 UCSC: uc003jmm.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Jamain, S., 2014	SNP: rs625487, rs633407 Haplotype: rs624097 - rs316762 - rs10512793()	Significant association of SNP in this gene with BD was observed.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

GO terms by PBA (count: 1)

GO terms by database search (count: 3)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs625487	chr5:41561271 - 41561271(1)		1(1/0/0)
rs633407	chr5:41571207 - 41571207(1)		1(1/0/0)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:41306954..41510628 View in gBrowse