SNP Report

Basic Info

Name	rs1610037 dbSNP Ensembl
Location	chr18:910634 - 910634(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.230032
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000579794); downstream_gene_variant(ENST00000269200, ENST00000450565); non_coding_transcript_exon_variant(ENST00000581602); non_coding_transcript_variant(ENST00000581602); upstream_gene_variant(ENST00000577358, ENST00000581719, ENST00000582554)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Lohoff, F. W., 2008 (a)	A/G		Genotypic P-value = 0.937, allelic P-value = 0.931 for BD wh...... Genotypic P-value = 0.937, allelic P-value = 0.931 for BD when compared with controls More...	No statistically significant association was found between B...... No statistically significant association was found between BPD and controls for any of the SNPs on the genotypic or allelic level. More...	Negative
Soria, V.,2010			X²-tests: allele P-value = 0.044, Model Recessive...... X²-tests: allele P-value = 0.044, Model Recessive, genotype P-value = 0.019, OR(95%CI)=1.83 (1.11-3.01) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	18p11	3(1/2/0)

SNPs in LD with rs1610037 (count: 0) View in gBrowse (chr18:910634..910634 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative