SNP Report

Basic Info

Name	rs1786581 dbSNP Ensembl
Location	chr18:11852183 - 11852183(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0539137
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000526991); downstream_gene_variant(ENST00000609238); intron_variant(ENST00000269162, ENST00000334049, ENST00000423027, ENST00000535121, ENST00000585642, ENST00000586474, ENST00000590228); non_coding_transcript_variant(ENST00000586474); upstream_gene_variant(ENST00000588284)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McNabb, L. D.,2005	C/T		Genotype distribution (bipolar disorder patients versus cont...... Genotype distribution (bipolar disorder patients versus controls), X² = 5.2, degrees of freedom = 2, P=0.07. Allele distribution (bipolar disorder patients versus controls), X² =3.56, degrees of freedom = 1, P = 0.06. More...	No significant association was observed. No significant association was observed.	Negative
Yosifova, A.,2009	C/T		Allelic association: P-value = 0.1 Allelic association: P-value = 0.1	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHMP1B	charged multivesicular body protein 1B	18p11.21	2(0/2/0)
GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18p11.22-p11.21	2(0/2/0)

SNPs in LD with rs1786581 (count: 0) View in gBrowse (chr18:11852183..11852183 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)