Gene Report

Basic Info
Approved Symbol CRY1
Previous Symbol PHLL1
Approved Name cryptochrome circadian clock 1
Previous Name cryptochrome 1 (photolyase-like)
Location 12q23-q24.1
Position chr12:106991364-107093829, -1
External Links HGNC: 2384
Entrez Gene: 1407
Ensembl: ENSG00000008405
UCSC: uc001tmi.4
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Soria, V.,2010 SNP: rs2287161, rs4640029, rs714359 Significant associations of CRY1 gene were found in BPD patients. Positive Comment on Study
Mansour, H. A., 2006 No significant association was detected in any sample using any test. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 40)

GO terms by PBA (count: 2)

GO terms by database search (count: 38)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)

Gene related interactors from protein-protein interactions data in HPRD (count: 8)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 3)

LD-proxies (count: 1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr12:106991364..107093829 View in gBrowse
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