Gene Report

Basic Info
Approved Symbol NTS
Approved Name neurotensin
Name Alias neuromedin N, "pro-neurotensin/neuromedin"
Location 12q21.31
Position chr12:85874295-85882992, 1
External Links HGNC: 8038
Entrez Gene: 4922
Ensembl: ENSG00000133636
UCSC: uc001tag.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Austin, J.,2000 Haplotype: (NTS_3A>G) - (NTS_166C>G)()
Other variant: NTS_166C>G, NTS_3A>G
No evidence for association was found, and our data therefore suggest that sequence variation in this gene does not make an important contribution to susceptibility to bipolar disorder. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 6)

GO terms by PBA (count: 0)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 7)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr12:85874295..85882992 View in gBrowse
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