SNP Report

Basic Info

Name	rs960914 dbSNP Ensembl
Location	chr8:28503460 - 28503460(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.361022
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000523546, ENST00000582598); intron_variant(ENST00000240093, ENST00000537916)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hashimoto, R.,2005(b)	T/C		Allelic association: P-value = 0.23 for BP Allelic association: P-value = 0.23 for BP	No significant associations were found in BD. No significant associations were found in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MIR4288	microRNA 4288	8	Mapped by Literature SNP
FZD3	frizzled class receptor 3	8p21	1(0/1/0)

SNPs in LD with rs960914 (count: 27) View in gBrowse (chr8:28503460..28584875 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10092491	intron_variant	1.0[CHB]; 1.0[JPT]
rs12681261		0.813[CHB]
rs13280925	intron_variant	0.848[CHB]; 1.0[JPT]
rs352210	intron_variant	1.0[CHB]; 1.0[JPT]
rs4415271	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs17440025		0.882[CHB]
rs352214	downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs6984655	intron_variant	1.0[CHB]; 1.0[JPT]
rs12677252	intron_variant	1.0[CHB]; 1.0[JPT]
rs164667	intron_variant	1.0[CHB]; 1.0[JPT]
rs352227	intron_variant	1.0[CHB]; 0.953[JPT]
rs2874941	intron_variant	0.839[CHB]; 1.0[JPT]
rs352222	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs352220	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs7001034	downstream_gene_variant; intron_variant; upstream_gene_variant	0.881[CHB]; 0.909[JPT]
rs7844545	downstream_gene_variant; intron_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs7842884	downstream_gene_variant; intron_variant	0.882[CHB]; 0.909[JPT]
rs164659		0.829[CHB]
rs352217	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs352436	intron_variant	1.0[CHB]; 1.0[JPT]
rs13271137	downstream_gene_variant	0.848[CHB]; 1.0[JPT]
rs164671		0.934[CHB]; 0.952[JPT]
rs6987561	intron_variant	1.0[CHB]; 1.0[JPT]
rs352226	intron_variant	1.0[CHB]; 0.906[JPT]
rs11783087	intron_variant	0.839[CHB]; 1.0[JPT]
rs893306	intron_variant	1.0[CHB]; 1.0[JPT]
rs10089889	downstream_gene_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Hashimoto, R.,2005(b)	Allelic association:P-value = 0.91 for SZ	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Hashimoto, R.,2005(b)	Allelic association:P-value = 0.61 for MDD	No association was observed in MDD.	Negative