BDgene

SNP Report

Basic Info
Name rs3916965 dbSNP Ensembl
Location chr13:105451011 - 105451011(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.36222
No. of Studies 6 (Positive: 2; Negative: 4; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Detera-Wadleigh, S. D., 2006 A/G Fisher P-value = 0.0001 for all Fisher P-value = 0.0001 for all When results are combined across studies and phenotypes, thi...... When results are combined across studies and phenotypes, this marker showed significant combined p value. More... Positive
Maheshwari, M.,2009 A/G TDT: Raw TDT P-value = 0.14, Adaptive permutation corrected ...... TDT: Raw TDT P-value = 0.14, Adaptive permutation corrected P-value = 1 More... No significant allelic association with BP was found No significant allelic association with BP was found Negative
Grigoroiu-Serbanescu, M.,2010 G/A Allelic association analysis: for non-psychotic patients, P-...... Allelic association analysis: for non-psychotic patients, P-value = 0.044, OR(95%CI)=1.82(1.01-3.28); for psychotic patients, P-value = 0.517, OR(95%CI)=0.9(0.66-1.24) More... Significant association was found in non-psychotic BP-I pati...... Significant association was found in non-psychotic BP-I patients. More... Positive
Gaysina, D.,2010 A/G chi-squared tests: allele P-value = 0.24 for UK sample; alle...... chi-squared tests: allele P-value = 0.24 for UK sample; allele P-value = 0.81 for Canadian sample. More... No significant association was observed in BD. No significant association was observed in BD. Negative
Bass, N. J.,2009 C/T chi-squared tests: for BP, allele, P-value > 0.05 chi-squared tests: for BP, allele, P-value > 0.05 No significant association was observed. No significant association was observed. Negative
Zhang, Z.,2009(a) A/G Allelic association: Odds ratio (95% CI)=0.89(0.74-1.07), P-...... Allelic association: Odds ratio (95% CI)=0.89(0.74-1.07), P-value = 0.229 More... No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DAOA D-amino acid oxidase activator 13q33.2 21(13/7/1)

SNPs in LD with rs3916965 (count: 0) View in gBrowse (chr13:105451011..105451011 )

Overlap with SZ from cross-disorder studies (count: 2)
Reference Statistical Result Description Result Category
Detera-Wadleigh, S. D., 2006 Fisher P-value = 0.0001 for all, P-value = 0.0002 for SCZ Only When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers and are highly significant (p<0.001) for three markers spanning more than 82 kb. Positive
Bass, N. J.,2009 chi-squared tests:for SCZ, allele, X2(1 d.f.)=2.101, P-value = 0.147 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)