SNP Report

Basic Info

Name	rs3916965 dbSNP Ensembl
Location	chr13:105451011 - 105451011(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.36222
No. of Studies	6 (Positive: 2; Negative: 4; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 6)

Reference	Allele Change	Statistical Values	Author Comments	Result Category
Detera-Wadleigh, S. D., 2006	A/G	Fisher P-value = 0.0001 for all Fisher P-value = 0.0001 for all	When results are combined across studies and phenotypes, thi...... When results are combined across studies and phenotypes, this marker showed significant combined p value. More...	Positive
Maheshwari, M.,2009	A/G	TDT: Raw TDT P-value = 0.14, Adaptive permutation corrected ...... TDT: Raw TDT P-value = 0.14, Adaptive permutation corrected P-value = 1 More...	No significant allelic association with BP was found No significant allelic association with BP was found	Negative
Grigoroiu-Serbanescu, M.,2010	G/A	Allelic association analysis: for non-psychotic patients, P-...... Allelic association analysis: for non-psychotic patients, P-value = 0.044, OR(95%CI)=1.82(1.01-3.28); for psychotic patients, P-value = 0.517, OR(95%CI)=0.9(0.66-1.24) More...	Significant association was found in non-psychotic BP-I pati...... Significant association was found in non-psychotic BP-I patients. More...	Positive
Gaysina, D.,2010	A/G	chi-squared tests: allele P-value = 0.24 for UK sample; alle...... chi-squared tests: allele P-value = 0.24 for UK sample; allele P-value = 0.81 for Canadian sample. More...	No significant association was observed in BD. No significant association was observed in BD.	Negative
Bass, N. J.,2009	C/T	chi-squared tests: for BP, allele, P-value > 0.05 chi-squared tests: for BP, allele, P-value > 0.05	No significant association was observed. No significant association was observed.	Negative
Zhang, Z.,2009(a)	A/G	Allelic association: Odds ratio (95% CI)=0.89(0.74-1.07), P-...... Allelic association: Odds ratio (95% CI)=0.89(0.74-1.07), P-value = 0.229 More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DAOA	D-amino acid oxidase activator	13q33.2	21(13/7/1)

SNPs in LD with rs3916965 (count: 0) View in gBrowse (chr13:105451011..105451011 )

Overlap with SZ from cross-disorder studies (count: 2)

Reference	Statistical Result	Description	Result Category
Detera-Wadleigh, S. D., 2006	Fisher P-value = 0.0001 for all, P-value = 0.0002 for SCZ Only	When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers and are highly significant (p<0.001) for three markers spanning more than 82 kb.	Positive
Bass, N. J.,2009	chi-squared tests:for SCZ, allele, X²(1 d.f.)=2.101, P-value = 0.147	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)