SNP Report

Basic Info

Name	rs9799720 dbSNP Ensembl
Location	chr4:8587621 - 8587621(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.0988419
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000382487, ENST00000509216); intron_variant(ENST00000514302); NMD_transcript_variant(ENST00000514302); non_coding_transcript_exon_variant(ENST00000504255); non_coding_transcript_variant(ENST00000504255)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	G/C		Allelic association: 1st screening: P-value = 0.038, 2nd scr...... Allelic association: 1st screening: P-value = 0.038, 2nd screening: P-value = 0.66, total: P-value = 0.035 More...	Significant association was observed in 1st screening and to...... Significant association was observed in 1st screening and total sample. More...	Positive
Underwood, S. L., 2006	C/G		no P-value given in the text no P-value given in the text	No single-marker association was detected with any other SNP...... No single-marker association was detected with any other SNP, in the males or in the individuals with BPAD. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GPR78	G protein-coupled receptor 78	4p16.1	2(2/0/0)

SNPs in LD with rs9799720 (count: 6) View in gBrowse (chr4:8586491..8587987 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9799378	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.814[CEU]
rs9799717	3_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.899[CEU]
rs9799809	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.899[CEU]
rs4696852	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.899[CEU]
rs9799721	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.899[CEU]
rs4391014	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Underwood, S. L., 2006	no P-value given in the text	No single-marker association was detected.	Negative

Overlap with MDD from cross-disorder studies (count: 0)