This work was supported by the State Administration of Foreign Experts Affairs of Chinese Academy of Sciences (CAS/SAFEA) International Partnership Program for Creative Research Teams (Grant No. Y2CX131003), the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KSCX2-EW-J-8), and Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

We thank all authors of the papers included in BDgene. Their valuable work is the basis of BDgene. We thank Dr. Kun-Lin Zhang for his valuable suggestions on parameter selection of pathway-based analysis for genome-wide association studies.