Gene Report

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Basic Info

Approved Symbol	UBXN7
Previous Symbol	UBXD7
Symbol Alias	KIAA0794
Approved Name	UBX domain protein 7
Previous Name	UBX domain containing 7
Location	3q29
Position	chr3:196347662-196432474, -1
External Links	HGNC: 29119 Entrez Gene: 26043 Ensembl: ENSG00000163960 UCSC: uc003fwm.4
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Schosser, A.,2011	SNP: rs4459932 Haplotype: rs6785339 - rs4459932()	No significant association was observed.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0008134	transcription factor binding	molecular function	IPI[18775313]	28
GO:0043130	ubiquitin binding	molecular function	IDA[18775313]	5
GO:0005654	nucleoplasm	cellular component	IDA	163
GO:0005515	protein binding	molecular function	IPI[18775313]	563
GO:0034098	Cdc48p-Npl4p-Ufd1p AAA ATPase complex	cellular component	IDA[18775313]	1
GO:0031625	ubiquitin protein ligase binding	molecular function	IDA[18775313]	25

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 4)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs4459932	chr3:196414790 - 196414790(1)	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs6583305	chr3:196391750 - 196391750(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant
rs6764533	chr3:196361593 - 196361593(1)	intron_variant; NMD_transcript_variant
rs6772164	chr3:196351278 - 196351278(1)	3_prime_UTR_variant; downstream_gene_variant

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Malhotra[2011]_2	chr3:197417247-198249463 (NCBI Build 36 (hg18))	832217	3q29	deletion	De Novo

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 3	chr3:0-198295559	2 (0/2/0)
3q29	chr3:192600000-198295559	2 (1/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:196347662..196432474 View in gBrowse