SNP Report

Basic Info

Name	rs1156044 dbSNP Ensembl
Location	chr18:9102142 - 9102142(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.195088
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000318388, ENST00000400033, ENST00000497577, ENST00000577703, ENST00000578850, ENST00000579126, ENST00000583375)
No. of Studies	3 (Positive: 2; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zhang, J.,2009	A/G	G	Allelic association: Odds ratio=0.908, P-value = 0.399; Geno...... Allelic association: Odds ratio=0.908, P-value = 0.399; Genotypic association: P-value = 0.489 More...	No significant association was observed No significant association was observed	Negative
Xu, C., 2008		A	Genotypic P-value = 0.000012, Bonferroni corrected genotypic...... Genotypic P-value = 0.000012, Bonferroni corrected genotypic P-value = 0.00007, Allelic P-value = 0.0020, Bonferroni corrected allelic P-value = 0.0130, OR (95% CI)=2.44 (1.36-4.36) . X²=9.39 More...	The A allele of the NDUFV2 SNP rs1156044 was significantly a...... The A allele of the NDUFV2 SNP rs1156044 was significantly associated (Bonferroni-corrected) with BD but differed in allele (rs1156044 G allele) from that previously reported as associated with BD. More...	Positive
Doyle, G. A.,2011	C/T	C	chi suqare test: genotype, X²=5.798, P-value = 0....... chi suqare test: genotype, X²=5.798, P-value = 0.055; allele C, X²=4.173, P-value = 0.041 More...	Significant association was found in allele association. Significant association was found in allele association.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	18p11.22	6(5/1/0)

SNPs in LD with rs1156044 (count: 24) View in gBrowse (chr18:9095069..9274638 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 24)

rs_ID	Functional Annotation	r²[population]
rs8092135	intron_variant	0.913[CEU]; 0.83[CHD]; 0.844[JPT]
rs10451358	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.829[CHD]; 0.844[JPT]
rs11660603	intron_variant; non_coding_transcript_variant	0.913[CEU]; 0.892[JPT]
rs4798789	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.8[JPT]
rs4130178	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.812[CHB]; 0.892[JPT]
rs2028656	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.912[CEU]; 0.844[JPT]
rs9652952	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.889[CEU]; 0.846[CHB]
rs874250	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.906[CEU]; 0.855[CHD]; 0.843[JPT]
rs6506648	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.913[CEU]; 0.83[CHD]; 0.844[JPT]
rs4798785	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.83[CHD]; 0.844[JPT]
rs4798771	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.906[CEU]; 0.892[JPT]
rs7235514	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.812[CHB]; 0.855[CHD]; 0.892[JPT]
rs7229883	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.81[CHB]; 0.83[CHD]; 0.892[JPT]
rs7231452	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.83[CHD]; 0.844[JPT]
rs998171	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.83[CHD]; 0.844[JPT]
rs2276095	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.913[CEU]; 0.812[CHB]; 0.892[JPT]
rs8083078	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.807[CHB]; 0.892[JPT]
rs1785560	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs8092878		1.0[CEU]; 1.0[TSI]; 0.894[CHB]; 0.8[JPT]
rs4798790	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.913[CEU]; 0.844[JPT]
rs6506644	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.913[CEU]; 0.812[CHB]; 0.83[CHD]; 0.892[JPT]
rs8084822		1.0[CEU]; 1.0[TSI]; 0.947[CHB]; 0.942[CHD]; 0.892[JPT]
rs8092613	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.913[CEU]; 0.812[CHB]; 0.892[JPT]
rs1443596	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.855[CHD]; 0.844[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)