Gene Report

Basic Info
Approved Symbol GPX3
Approved Name glutathione peroxidase 3
Previous Name glutathione peroxidase 3 (plasma)
Location 5q33.1
Position chr5:151020438-151028993, 1
External Links HGNC: 4555
Entrez Gene: 2878
Ensembl: ENSG00000211445
UCSC: uc021yga.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fullerton, J. M.,2010 SNP: rs3792797, rs8177435
Haplotype: rs3792797 - rs8177435 - rs5746136 - rs4880(), rs3792797 - rs4880()
We provide evidence that an interaction at both the genotype and haplotype level between SOD2 and GPX3 further increases disease risk. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 0)

GO terms by database search (count: 12)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr5:151020438..151028993 View in gBrowse
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