SNP Report

Basic Info

Name	rs969486 dbSNP Ensembl
Location	chr11:13381588 - 13381588(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.386182
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000529390); intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403482, ENST00000403510, ENST00000472842, ENST00000524392); NMD_transcript_variant(ENST00000524392); non_coding_transcript_variant(ENST00000472842)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A., 2006	C/T		TDT P-value = 0.994 in the samples combined, Pittsburgh Tren...... TDT P-value = 0.994 in the samples combined, Pittsburgh Trends test=0.501 for BDI More...	The loci tested did not show significant differences between...... The loci tested did not show significant differences between sites in the transmission rate. More...	Negative
Soria, V.,2010			X²-tests: allele P-value = 0.022, Model Log-addit...... X²-tests: allele P-value = 0.022, Model Log-additive, genotype P-value = 0.015, OR(95%CI)=0.69 (0.51-0.93) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)

SNPs in LD with rs969486 (count: 0) View in gBrowse (chr11:13381588..13381588 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mansour, H. A., 2006	not analyzed for Pittsburgh SZ/SZA		Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative