SNP Report

Basic Info

Name	rs4880 dbSNP Ensembl
Location	chr6:159692840 - 159692840(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.410743
Functional Annotation	5_prime_UTR_variant; missense_variant; NMD_transcript_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000337404, ENST00000367054, ENST00000367055, ENST00000444946, ENST00000452684, ENST00000535561, ENST00000538183, ENST00000545162, ENST00000546260) SIFT Annotation: tolerated - low confidence(ENST00000546260); tolerated(ENST00000337404, ENST00000367054, ENST00000367055, ENST00000444946, ENST00000452684, ENST00000535561, ENST00000538183, ENST00000545162)
Consequence to Transcript	5_prime_UTR_variant(ENST00000401980, ENST00000537657, ENST00000546087); missense_variant(ENST00000337404, ENST00000367054, ENST00000367055, ENST00000444946, ENST00000452684, ENST00000535561, ENST00000538183, ENST00000545162, ENST00000546260); NMD_transcript_variant(ENST00000546260); upstream_gene_variant(ENST00000535459, ENST00000540491, ENST00000541573)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fullerton, J. M.,2010		A	Allelic association: X²=2.207, P-value = 0.137, O...... Allelic association: X²=2.207, P-value = 0.137, OR=0.844 for broad model; X²=1.649, P-value = 0.199, OR=0.851 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SOD2	superoxide dismutase 2, mitochondrial	6q25	2(1/1/0)

SNPs in LD with rs4880 (count: 0) View in gBrowse (chr6:159692840..159692840 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)