SNP Report

Basic Info

Name	rs726908 dbSNP Ensembl
Location	chr8:32201112 - 32201112(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.332468
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000517967, ENST00000518104, ENST00000519301, ENST00000520407, ENST00000523534); non_coding_transcript_variant(ENST00000517967)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.5682 for BP, Individual P-value = 0.5...... Individual P-value = 0.5682 for BP, Individual P-value = 0.5578 for SCZ and BP More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs726908 (count: 12) View in gBrowse (chr8:32146658..32214227 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10093657	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.85[CEU]; 0.829[TSI]
rs11780219	intron_variant; upstream_gene_variant	0.85[CEU]; 0.829[TSI]
rs1481761	intron_variant	1.0[CEU]
rs2881472	intron_variant; upstream_gene_variant	0.962[CEU]
rs12550195	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs13249590	intron_variant	0.962[CEU]; 1.0[TSI]
rs2068226	intron_variant	0.85[CEU]
rs10097263	intron_variant; non_coding_transcript_variant	0.847[CEU]; 0.81[TSI]
rs10093107	intron_variant; upstream_gene_variant	0.962[CEU]; 1.0[TSI]
rs4733303	intron_variant	0.839[CEU]; 0.829[TSI]
rs1383964	intron_variant	0.924[CEU]; 0.933[TSI]
rs720684	intron_variant; non_coding_transcript_variant	0.96[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.6665 for SCZ , Individual P-value = 0.5578 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)