SNP Report

Basic Info

Name	rs1152230 dbSNP Ensembl
Location	chr19:49930246 - 49930246(1)
Variant Alleles	G/A/C/T
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.291134
Functional Annotation	5_prime_UTR_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000596658); intron_variant(ENST00000423777, ENST00000451973, ENST00000595125, ENST00000597227, ENST00000600336); NMD_transcript_variant(ENST00000451973); upstream_gene_variant(ENST00000341114, ENST00000352066, ENST00000422090, ENST00000578027, ENST00000593652, ENST00000594673, ENST00000595463, ENST00000595948, ENST00000596011, ENST00000596022, ENST00000596217, ENST00000596437, ENST00000596680, ENST00000597029, ENST00000597295, ENST00000597723, ENST00000597814, ENST00000598301, ENST00000599186, ENST00000599560, ENST00000599567, ENST00000599788, ENST00000599830, ENST00000600583, ENST00000600935, ENST00000601665, ENST00000601717)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kakiuchi, C., 2007 (b)	A/G		Fisher's exact test, genotypic P-value = 0.367, allelic P-va...... Fisher's exact test, genotypic P-value = 0.367, allelic P-value = 0.514 in MDMD samples, Fisher's exact test, genotypic P-value = 0.729, allelic P-value = 0.485 in MPS samples, Fisher's exact test, genotypic P-value = 0.763, allelic P-value = 0.997 in total samples; TDT P-value = 0.783, X²=0.076 in NIMH trios More...	There were no significant differences in both genotype and a...... There were no significant differences in both genotype and allele frequencies in both of total samples and independently collected age-matched samples. TDT analysis also showed no association of the SNP to the illness. More...	Negative

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
IL4I1	interleukin 4 induced 1	19q13.3-q13.4	Mapped by Literature SNP
NUP62	nucleoporin 62kDa	19q13.33	Mapped by Literature SNP
ATF5	activating transcription factor 5	19q13.33	1(0/1/0)

SNPs in LD with rs1152230 (count: 0) View in gBrowse (chr19:49930246..49930246 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)