Gene Report

Basic Info
Approved Symbol PROK2
Symbol Alias PK2, BV8, MIT1, KAL4
Approved Name prokineticin 2
Name Alias protein Bv8 homolog
Location 3p21.1
Position chr3:71771656-71785206, -1
External Links HGNC: 18455
Entrez Gene: 60675
Ensembl: ENSG00000163421
UCSC: uc003dpa.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kishi, T.,2009(c) SNP: rs10865660, rs1316780, rs1374913, rs3796224
Haplotype: rs1316780 - rs10865660 - rs3796224 - rs1374913()
In this study, we could detect no evidence of genetic association between PROK2 and BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 15)

GO terms by PBA (count: 1)

GO terms by database search (count: 14)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 9)

Literature-origin SNPs (count: 4)

LD-proxies (count: 5)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr3:71771656..71785206 View in gBrowse
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