SNP Report

Basic Info

Name	rs7007662 dbSNP Ensembl
Location	chr8:32095229 - 32095229(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.437101
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000518104, ENST00000519301, ENST00000520407, ENST00000521463, ENST00000523534, ENST00000523743); non_coding_transcript_variant(ENST00000521463, ENST00000523743)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.963 for BP, Individual P-value = 0.79...... Individual P-value = 0.963 for BP, Individual P-value = 0.7981 for SCZ and BP More...		Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1-IT1	NRG1 intronic transcript 1	8p12	Mapped by Literature SNP
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs7007662 (count: 4) View in gBrowse (chr8:32091348..32107672 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6993043	intron_variant; non_coding_transcript_variant	0.809[CEU]
rs16878794	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs11776959	intron_variant; non_coding_transcript_variant	0.851[CEU]
rs10954827	intron_variant; non_coding_transcript_variant	0.855[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.7023 for SCZ , Individual P-value = 0.7981 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)