Search SNP
Search Gene
Search CNV
Search Haplotype
Search Other Variant
Search Region
Search Pathway
Search Study
SNP Report
Basic Info
| Name | rs4935752 dbSNP Ensembl | ||
|---|---|---|---|
| Location | chr11:120818410 - 120818410(1) | ||
| Variant Alleles | A/C | ||
| Ancestral Allele | A | ||
| Minor Allele | C | ||
| Minor Allele Frequence | 0.281949 | ||
| Functional Annotation | downstream_gene_variant; intron_variant; non_coding_transcript_variant. | ||
| Consequence to Transcript | downstream_gene_variant(ENST00000526536); intron_variant(ENST00000438375, ENST00000527524, ENST00000533291); non_coding_transcript_variant(ENST00000533291) | ||
| No. of Studies | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
| Overlap with SZ? | YES | ||
| Overlap with MDD? | NO | ||
SNP related studies (count: 1)
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| GRIK4 | glutamate receptor, ionotropic, kainate 4 | 11q23.3 | 2(1/1/0) |
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 10)
Overlap with SZ from cross-disorder studies (count: 1)
| Reference | Statistical Result | Description | Result Category |
|---|---|---|---|
| Pickard, B. S., 2006 | P-value = 0.001 between SCZ cases and controls; P-value = 0.022 between all cases and controls; Best global P-value (permutation corrected)=0.03 | showed significant association with schizophrenia; SNP 15 remained significantly associated with schizophrenia after permutation analysis to counter multiple testing errors | Positive |
Overlap with MDD from cross-disorder studies (count: 0)