BDgene

SNP Report

Basic Info
Name rs4935752 dbSNP Ensembl
Location chr11:120818410 - 120818410(1)
Variant Alleles A/C
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.281949
Functional Annotation downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000526536); intron_variant(ENST00000438375, ENST00000527524, ENST00000533291); non_coding_transcript_variant(ENST00000533291)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Pickard, B. S., 2006 A/C P-value = 0.584 between BPD cases and controls; P-value = 0...... P-value = 0.584 between BPD cases and controls; P-value = 0.022 between all cases and controls More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRIK4 glutamate receptor, ionotropic, kainate 4 11q23.3 2(1/1/0)

SNPs in LD with rs4935752 (count: 10) View in gBrowse (chr11:120817890..120853613 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Pickard, B. S., 2006 P-value = 0.001 between SCZ cases and controls; P-value = 0.022 between all cases and controls; Best global P-value (permutation corrected)=0.03 showed significant association with schizophrenia; SNP 15 remained significantly associated with schizophrenia after permutation analysis to counter multiple testing errors Positive

Overlap with MDD from cross-disorder studies (count: 0)