SNP Report

Basic Info

Name	rs4430518 dbSNP Ensembl
Location	chr11:120852724 - 120852724(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.32488
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000438375, ENST00000527524, ENST00000533291); non_coding_transcript_variant(ENST00000533291)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pickard, B. S., 2006	G/T		P-value = 0.653 between BPD cases and controls; P-value = 0...... P-value = 0.653 between BPD cases and controls; P-value = 0.244 between all cases and controls More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRIK4	glutamate receptor, ionotropic, kainate 4	11q23.3	2(1/1/0)

SNPs in LD with rs4430518 (count: 3) View in gBrowse (chr11:120852724..120863710 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4344499	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.838[CEU]; 0.814[TSI]
rs10892631	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.876[TSI]
rs3901285	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.876[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pickard, B. S., 2006	P-value = 0.015 between SCZ cases and controls; P-value = 0.244 between all cases and controls	showed significant association with schizophrenia	Positive

Overlap with MDD from cross-disorder studies (count: 0)