Gene Report

Basic Info
Approved Symbol FABP7
Symbol Alias B-FABP, BLBP
Approved Name fatty acid binding protein 7, brain
Name Alias brain lipid binding protein
Location 6q22-q23
Position chr6:122779475-122784074, 1
External Links HGNC: 3562
Entrez Gene: 2173
Ensembl: ENSG00000164434
UCSC: uc003pzf.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Iwayama, Y., 2010 SNP: rs12662030, rs2279381, rs2279382, rs4247671, rs6899351, rs6904500, rs6919681, rs7752838, rs9372716, rs9401594, rs9401595, rs9401596, rs9482286, rs9490550
Haplotype: rs2279382 - rs2279381 - rs7752838(TCA), rs2279382 - rs2279381 - rs7752838(TCG), rs2279382 - rs2279381 - rs7752838(GTG), rs2279382 - rs2279381 - rs7752838(GCG), rs4247671 - rs12662030 - rs9372716(AAT), rs4247671 - rs12662030 - rs9372716(AAC), rs4247671 - rs12662030 - rs9372716(ACC), rs4247671 - rs12662030 - rs9372716(GAC), rs6899351 - rs6919681 - rs6904500(TAT), rs6899351 - rs6919681 - rs6904500(TAC), rs6899351 - rs6919681 - rs6904500(TGC), rs6899351 - rs6919681 - rs6904500(CGC), rs9490550 - rs9401596(TG), rs9490550 - rs9401596(GA), rs9490550 - rs9401596(GG)
Three single nucleotide polymorphisms (SNPs) from FABP7 showed nominal association with bipolar disorder, and haplotypes of the same gene showed empirical associations with bipolar disorder even after correction of multiple testing. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 2)

GO terms by database search (count: 11)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 16)

Literature-origin SNPs (count: 14)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 3)

Gene relationship with MDD

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Region: chr6:122779475..122784074 View in gBrowse
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