SNP Report

Basic Info

Name	rs6693503 dbSNP Ensembl
Location	chr1:19660801 - 19660801(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.437899
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000289749, ENST00000375136, ENST00000425400, ENST00000427894, ENST00000428975, ENST00000439664, ENST00000451758, ENST00000548815, ENST00000602293, ENST00000602384, ENST00000602450, ENST00000602662, ENST00000615215, ENST00000618761, ENST00000621723, ENST00000622566); upstream_gene_variant(ENST00000289753)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Fukuo, Y.,2010	A>G		Association analysis: genotype P-value = 0.893, allele P-val...... Association analysis: genotype P-value = 0.893, allele P-value = 0.751 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	1p36-p35	3(1/2/0)
NBL1	neuroblastoma 1, DAN family BMP antagonist	1p36.3-p36.2	Mapped by Literature SNP
MINOS1-NBL1	MINOS1-NBL1 readthrough	1p36.13	Mapped by Literature SNP

SNPs in LD with rs6693503 (count: 3) View in gBrowse (chr1:19660801..19680394 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4912141	intron_variant	0.822[CHD]
rs10917513	downstream_gene_variant	0.839[CHD]
rs10917509	5_prime_UTR_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Fukuo, Y.,2010	Association analysis:genotype P-value = 0.977, allele P-value = 0.904	No significant association was observed.	Negative