BDgene

SNP Report

Basic Info
Name rs3916967 dbSNP Ensembl
Location chr13:105464999 - 105464999(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.362819
Functional Annotation downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000610818, ENST00000613021); intron_variant(ENST00000448407); non_coding_transcript_variant(ENST00000448407); upstream_gene_variant(ENST00000329625, ENST00000375936, ENST00000471432, ENST00000473269, ENST00000488534, ENST00000489237, ENST00000559369, ENST00000595812, ENST00000600388, ENST00000601240, ENST00000618629)
No. of Studies 4 (Positive: 2; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 4)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Hukic, D. S.,2013 C/T BP1 CMS vs. ABD controls: P-value = 0.029,empirical p-value ...... BP1 CMS vs. ABD controls: P-value = 0.029,empirical p-value =0.026,empirical p-value2 = 0.28,OR[95%CI] = 0.78[0.66–1.0] More... Significant association was observed. Significant association was observed. Positive
Detera-Wadleigh, S. D., 2006 A/G Fisher P-value = 0.0734 for all Fisher P-value = 0.0734 for all Negative
Bass, N. J.,2009 A/G chi-squared tests: for BP, allele, P-value > 0.05 chi-squared tests: for BP, allele, P-value > 0.05 No significant association was observed. No significant association was observed. Negative
Grigoroiu-Serbanescu, M.,2010 A/G Allelic association analysis: for non-psychotic patients, P-...... Allelic association analysis: for non-psychotic patients, P-value = 0.043, OR(95%CI)=1.82(1.01-3.28); for psychotic patients, P-value = 0.517, OR(95%CI)=0.9(0.66-1.24) More... Significant association was found in non-psychotic BP-I pati...... Significant association was found in non-psychotic BP-I patients. More... Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DAOA-AS1 DAOA antisense RNA 1 13q33.2 Mapped by Literature SNP
DAOA D-amino acid oxidase activator 13q33.2 21(13/7/1)

SNPs in LD with rs3916967 (count: 12) View in gBrowse (chr13:105448044..105464999 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 12)


Overlap with SZ from cross-disorder studies (count: 2)
Reference Statistical Result Description Result Category
Detera-Wadleigh, S. D., 2006 Fisher P-value = 0.0734 for all, P-value = 0.0734 for SCZ Only Negative
Bass, N. J.,2009 chi-squared tests:for SCZ, allele, X2(1 d.f.)=3.675, P-value = 0.055 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)