SNP Report

Basic Info

Name	rs3916967 dbSNP Ensembl
Location	chr13:105464999 - 105464999(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.362819
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000610818, ENST00000613021); intron_variant(ENST00000448407); non_coding_transcript_variant(ENST00000448407); upstream_gene_variant(ENST00000329625, ENST00000375936, ENST00000471432, ENST00000473269, ENST00000488534, ENST00000489237, ENST00000559369, ENST00000595812, ENST00000600388, ENST00000601240, ENST00000618629)
No. of Studies	4 (Positive: 2; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 4)

Reference	Allele Change	Statistical Values	Author Comments	Result Category
Hukic, D. S.,2013	C/T	BP1 CMS vs. ABD controls: P-value = 0.029,empirical p-value ...... BP1 CMS vs. ABD controls: P-value = 0.029,empirical p-value =0.026,empirical p-value2 = 0.28,OR[95%CI] = 0.78[0.66â€“1.0] More...	Significant association was observed. Significant association was observed.	Positive
Detera-Wadleigh, S. D., 2006	A/G	Fisher P-value = 0.0734 for all Fisher P-value = 0.0734 for all		Negative
Bass, N. J.,2009	A/G	chi-squared tests: for BP, allele, P-value > 0.05 chi-squared tests: for BP, allele, P-value > 0.05	No significant association was observed. No significant association was observed.	Negative
Grigoroiu-Serbanescu, M.,2010	A/G	Allelic association analysis: for non-psychotic patients, P-...... Allelic association analysis: for non-psychotic patients, P-value = 0.043, OR(95%CI)=1.82(1.01-3.28); for psychotic patients, P-value = 0.517, OR(95%CI)=0.9(0.66-1.24) More...	Significant association was found in non-psychotic BP-I pati...... Significant association was found in non-psychotic BP-I patients. More...	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DAOA-AS1	DAOA antisense RNA 1	13q33.2	Mapped by Literature SNP
DAOA	D-amino acid oxidase activator	13q33.2	21(13/7/1)

SNPs in LD with rs3916967 (count: 12) View in gBrowse (chr13:105448044..105464999 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs4581580		1.0[CEU]; 0.977[TSI]
rs9558553		1.0[CEU]; 0.977[TSI]
rs1341403	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.953[TSI]
rs9519675	downstream_gene_variant; upstream_gene_variant	0.848[CEU]
rs9555168		1.0[CEU]
rs6491959		1.0[CEU]
rs6491960		1.0[CEU]
rs1126113		1.0[CEU]; 0.977[TSI]
rs9519679	downstream_gene_variant; upstream_gene_variant	0.849[CEU]
rs1126115		1.0[CEU]
rs4772687	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.846[CEU]
rs7331194		0.958[CEU]

Overlap with SZ from cross-disorder studies (count: 2)

Reference	Statistical Result	Description	Result Category
Detera-Wadleigh, S. D., 2006	Fisher P-value = 0.0734 for all, P-value = 0.0734 for SCZ Only		Negative
Bass, N. J.,2009	chi-squared tests:for SCZ, allele, X²(1 d.f.)=3.675, P-value = 0.055	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)