SNP Report

Basic Info

Name	rs435136 dbSNP Ensembl
Location	chr12:119813576 - 119813576(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.254193
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000261833, ENST00000392521, ENST00000536325, ENST00000612548)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Lyons-Warren, A.,2005	T/C		FBAT: P-value = 0.012 FBAT: P-value = 0.012	Significant associations were found . Significant associations were found .	Positive
Yosifova, A.,2009	A/G		Allelic association: P-value = 0.26 Allelic association: P-value = 0.26	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CIT	citron rho-interacting serine/threonine kinase	12q24.23	2(1/1/0)

SNPs in LD with rs435136 (count: 15) View in gBrowse (chr12:119798678..119838394 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs450902	intron_variant	0.955[CEU]; 0.864[TSI]
rs4767849	intron_variant	1.0[CEU]; 0.954[TSI]
rs10774516	intron_variant	0.955[CEU]
rs4767848	intron_variant	1.0[CEU]; 0.976[TSI]
rs377876	intron_variant	0.954[CEU]
rs280582	intron_variant	0.955[CEU]; 0.865[TSI]
rs7308076	intron_variant	1.0[CEU]; 0.976[TSI]
rs740032	intron_variant	1.0[CEU]; 0.977[TSI]
rs10744743	intron_variant; upstream_gene_variant	1.0[CEU]
rs1182807	intron_variant	0.955[CEU]; 0.952[TSI]
rs4767847	intron_variant; upstream_gene_variant	1.0[CEU]
rs203340	intron_variant; non_coding_transcript_variant	0.869[CEU]; 0.862[TSI]
rs10774514	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs3847960	intron_variant	1.0[CEU]; 0.91[TSI]
rs10774515	intron_variant; upstream_gene_variant	0.954[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)